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Diablo 4 Season 12 Ultimate Runes Farming Guide | Utilizing Kurast Undercity and more tricks to maximize the drops instantly!

Mar 25, 2026 Author: D4gold

The release of Diablo 4: Vessel of Hatred DLC, players have gained a new method to enhance their characters: runes! Even now, in Season 12, these runes continue to play an indispensable role.

Consequently, besides gold and essential gear, runes require you to engage in rapid and extensive farming throughout the current season.

Given the general system optimizations introduced in every season, the specific methods for farming runes also undergo minor adjustments. Based on the changes implemented in Season 12, we present to you the latest guide on how to acquire runes.

Diablo 4 Season 12 Ultimate Runes Farming Guide | Utilizing Kurast Undercity and more tricks to maximize the drops instantly!

Season 12 changes related to runes

All Diablo 4 runes are categorized into three rarity tiers: magic, rare, and legendary, ranging from lowest to highest rarity. Naturally, legendary runes are the most difficult to obtain.

Unfortunately, the overall reduction in item drop rates introduced in Season 12 also extends to legendary runes. This means that, at least until the launch of the game's second expansion, the probability of acquiring high-tier runes or crafting Runewords remains relatively low.

However, there is good news: the bugs preventing some runes from functioning correctly have been fixed. Furthermore, the generation rate of offerings has been increased to improve the overall efficiency of Runewords.

This improvement addresses a core mechanic introduced in Diablo 4. Individual runes cannot function in isolation; they must be combined into a Runeword consisting of one rune of Ritual and one rune of Invocation.

The former generates the offerings once specific conditions are met, while the latter consumes offerings to trigger the final bonus effect.

Prerequisites for farming runes

Since this mechanic was introduced to the game via VoH expansion, you must own the expansion to both acquire and utilize runes. Additionally, you must complete Fundament of Faith campaign chapter within the expansion before runes will begin to drop.

It is worth noting that as you continue to progress through Vessel of Hatred campaign and defeat the first boss, you will receive your initial set of runes; however, this specific source of runes can only be utilized once.

Defeating world bosses

Once you have completed or skipped the main campaign of Diablo 4, the game will send you a system notification whenever a world boss appears. You can then simply travel to the location of the currently rotating world boss to begin farming.

The loot tables for all world bosses include runes, as well as other general loot; however, the quantity and quality of these drops are randomized:

  • Unique and Legendary items
  • Runes
  • Exquisite Blood
  • Tribute of Radiance
  • Tribute of Ascendance
  • Scattered Prism

Additionally, the three specific World Bosses each possess their own exclusive drops. These special rewards, which can yield extra gold, gems, or other items, are granted only upon your first successful kill of that boss each week.

  • Ashava the Pestilent: Ashava's Spoils
  • Avarice, The Gold Cursed: Avarice's Spoils
  • Wandering Death, Death Given Life: Wandering Death's Spoils

Defeating lair bosses

These bosses are more challenging than world bosses; there are a total of nine such encounters, and they can only be challenged after unlocking Torment 1.

Lair boss battles can be initiated at any time; however, you must first collect the corresponding lair keys in order to open the hoards you receive upon victory.

Regarding loot, all lair bosses drop exclusively runes and unique items. While the number of Unique items increases with higher difficulty tiers, only a single rune will ever drop per encounter:

  • Torment 1: 3 Uniques + 1 rune
  • Torment 2: 4 Uniques + 1 rune
  • Torment 3: 5 Uniques + 1 rune
  • Torment 4: 7 Uniques + 1 rune

Therefore, to maximize the value of your lair boss runs, we highly recommend prioritizing Belial, as he offers the highest probability of dropping Mythic Unique items. The following lists the keys and quantities required to unlock each boss's hoard (per attempt):

  • Varshan: 12 Malignant Hearts
  • Grigoire: 12 Living Steel
  • The Beast in the Ice: 12 Distilled Fear
  • Lord Zir: 12 Exquisite Blood
  • Urivar: 12 Judicator's Masks
  • Duriel: 3 Shards of Agony
  • Andariel: 3 Pincushioned Dolls
  • Harbinger of Hatred: 3 Abhorrent Hearts
  • Belial: 2 Betrayer's Husks

Related: The Best Monster Farming Method in Diablo IV Season 12 Based on Seasonal Reputation System | Maximizing Equipment and Resource Drop Rates

Clearing Kurast Undercity

This dungeon is exclusive to VoH expansion; however, since you are already able to begin farming runes, this should not pose a problem for you, simply ensure that you have completed Reunion quest and that your character is level 15 or higher.

Kurast Undercity is characterized as a time-limited, multi-tiered dungeon. You must defeat a sufficient number of enemies within a set time limit to accumulate Attunement points; rewards are calculated and distributed based on your total points once the run concludes.

To maximize your available challenge time, the game features a mechanic where defeating enemies restores a certain amount of time. Higher-level enemies restore more time:

  • Minor Afflicted: 1 Second
  • Lesser Afflicted: 8 Seconds
  • Named Lesser Afflicted: 14 Seconds
  • Afflicted Object: 15 Seconds
  • Greater Afflicted: 30 Seconds
  • Mini-Boss Afflicted: 30 Seconds

Additionally, you may encounter Spirit or Grand Beacons within Kurast Undercity. These trigger additional events or spawn enemies that increase the difficulty of the challenge, but they also grant you new combat buffs and bonuses to loot drops.

Furthermore, to ensure you obtain the maximum number of runes from this dungeon, you should first farm Tributes of Harmony in advance and then offer them at Spirit Brazier.

Doing so will allow you to receive double the amount of runes when your loot rewards are calculated at the end of the run.

Currently, the primary sources for these tributes are The Pit and Whisper Caches. The former is another time-limited, multi-tiered dungeon, while the latter are rewards obtained by completing Tree of Whispers bounty quests.

Upon completing Tree of Whispers quests, you will receive a variable amount of Grim Favors; every ten Grim Favors can be redeemed for one Whisper Cache.

Crafting runes

The prerequisite for using this method is having a sufficient number of duplicate, unused runes. Locate Jeweler in-game; you can then craft a new rune by consuming three runes of the same rarity along with 4,000 gold.

The above covers all the information you need to know regarding farming runes in Diablo 4 Season 12. Given the rather unforgiving drop rates, you had better make every moment count!

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